Chicken And Biscuit Casserole

Name: Chicken And Biscuit Casserole
Prep time: 20 min
Cook time: 45 min
Total time: 1 h 5 min
Yield: 6 servings
Ingredients: 3 cups cooked chicken, shredded; 1 cup frozen mixed vegetables; 1 can cream of chicken soup; 1/2 cup milk; 1 teaspoon garlic powder; 1 teaspoon onion powder; 1 teaspoon black pepper; 1 can refrigerated biscuits; 1 cup shredded cheddar cheese

Highlighted under: Classic Collection

I absolutely love making Chicken and Biscuit Casserole for family gatherings. It's one of those dishes that brings everyone together at the table. The combination of tender chicken, vegetables, and flaky biscuits creates a comforting meal that warms the heart. Plus, it's incredibly easy to whip up, making it perfect for both busy weeknights and special occasions. I often add a few extra spices to elevate the flavor, and each time I serve it, the empty dishes around the table tell me I’ve hit a home run!

Created by

Briony Ashcroft

Last updated on 2026-01-24T09:09:34.398Z

This Chicken and Biscuit Casserole has been a family favorite for years. I discovered the recipe during a rainy day, craving something warm and hearty. After a few tweaks, like adding my favorite herbs, it transformed into a classic crowd-pleaser. The challenge was getting just the right balance of sauce and biscuit, but once I mastered that, it became our go-to dish.

One tip I found essential is to let the casserole rest for a few minutes before serving. This allows the flavors to meld together and makes portioning a breeze. Each bite brings a comforting combination of creamy chicken and fluffy biscuit that I know everyone will love.

        Why You'll Love This Recipe
        Comforting, hearty flavors that evoke nostalgia
Flaky biscuits that soak up the savory sauce
Perfect for leftovers or meal prep

      

Ingredient Insights

The foundation of this Chicken and Biscuit Casserole is, of course, the chicken itself. Shredded cooked chicken not only contributes a comforting texture but also acts as a canvas for all the accompanying flavors. For a boost in taste, use rotisserie chicken; its smoky, seasoned skin adds a depth that elevates the dish. If you’re looking for a lighter alternative, consider using turkey instead, which works just as well in this recipe.

Frozen mixed vegetables are a great time-saver in this casserole. However, if you prefer fresh produce, you can use a mix of chopped carrots, peas, and green beans. Just be sure to lightly steam them before adding to the casserole so they retain their vibrant colors and crunchy texture after baking. This flexibility allows you to use seasonal vegetables or those you have on hand, making this dish perfect for using up leftovers.

Making the Perfect Biscuit Topping

The biscuit topping is a crucial element for both texture and flavor. For an even flakier result, consider using buttermilk biscuits instead of regular ones, as the acidity in buttermilk enhances the biscuit's tenderness. If you’re feeling adventurous, you can also add herbs like thyme or rosemary to the biscuit dough before baking, which will complement the overall savory profile of the casserole beautifully.

When arranging the biscuit halves on top of the chicken mixture, make sure to leave small gaps between them. This allows the steam to escape while baking, leading to a perfectly cooked biscuit that is golden brown on the outside yet soft and pillowy on the inside. Keep an eye on them during the last few minutes of baking, as the perfect biscuit will have a beautiful golden edge and will pull away slightly from the casserole beneath.

Ingredients

Gather these ingredients for a delicious Chicken and Biscuit Casserole:

Ingredients

3 cups cooked chicken, shredded
1 cup frozen mixed vegetables
1 can cream of chicken soup
1/2 cup milk
1 teaspoon garlic powder
1 teaspoon onion powder
1 teaspoon black pepper
1 can refrigerated biscuits
1 cup shredded cheddar cheese

Make sure to have these on hand before you start cooking!

Instructions

Follow these steps for a perfect Chicken and Biscuit Casserole:

Preheat Oven

Preheat your oven to 350°F (175°C).

Combine Ingredients

In a large mixing bowl, combine the shredded chicken, frozen vegetables, cream of chicken soup, milk, garlic powder, onion powder, and black pepper. Stir until well mixed.

Transfer to Baking Dish

Pour the mixture into a greased 9x13 inch baking dish and spread it evenly.

Top with Biscuits

Open the can of biscuits and cut each biscuit in half. Arrange the biscuit halves on top of the chicken mixture. Sprinkle shredded cheddar cheese over the biscuits.

Bake

Bake in the preheated oven for 30-35 minutes, or until the biscuits are golden brown and cooked through.

Serve

Let the casserole rest for 5 minutes before serving. Enjoy your delicious meal!

Enjoy your delightful Chicken and Biscuit Casserole!

Pro Tips

For an extra flavor boost, try adding fresh herbs like thyme or rosemary to the chicken mixture.

Storing and Reheating

This casserole stores wonderfully, making it an excellent choice for meal prep. To store leftovers, allow the casserole to cool completely, then cover it tightly with plastic wrap or aluminum foil. It can be kept in the refrigerator for up to 3 days. If you want to extend its shelf life, consider freezing it. To freeze, section the casserole into individual portions and transfer them to airtight containers, where they'll keep well for up to two months.

When reheating, it’s best to allow the casserole to thaw overnight in the refrigerator if frozen. For reheating, place it in a preheated oven at 350°F (175°C) for about 20-25 minutes, or until heated through. If the biscuits start to become too brown, you can cover the casserole with foil to prevent burning while ensuring the center gets warm. This way, every bite will taste just as good as when it was first made.

Variations to Try

If you're looking to switch things up, consider experimenting with different proteins such as diced ham or cooked sausage, which can add a unique twist to the casserole. For those who love a bit of spice, adding chopped green chilies or jalapeños can introduce a delightful kick that contrasts beautifully with the creamy sauce. Vegetarians can easily adapt this recipe by replacing chicken with a medley of hearty vegetables like mushrooms or eggplant along with some white beans for additional protein.

To enhance the flavor profile even further, think about incorporating a splash of hot sauce into the chicken mixture before baking, or top the casserole with a sprinkle of paprika or crushed red pepper flakes for that additional flavor pop. These variations ensure that you can enjoy this comforting dish with a new twist every time.

Questions About Recipes

→ Can I use frozen chicken instead of cooked?

Yes, you can cook frozen chicken breasts and shred them to use in this recipe.

→ What other vegetables can I add?

You can add any vegetables you like, such as peas, carrots, or even broccoli.

→ Can I make this ahead of time?

Absolutely! You can prepare the chicken mixture and refrigerate it, then add the biscuits just before baking.

→ How do I store leftovers?

Store any leftovers in an airtight container in the refrigerator for up to 3 days.